Either water, 0.05% glycopyrronium bromide solution (or a stronger concentration) or botox solution can be administered via iontophoresis, in order of the severity of condition.
Maintenance therapy should be carried out twice or three or more times a
week to maintain constant dryness with water. "Complete abolition of sweating was found to last one to two weeks and sweating quickly returned without maintenance therapy." - ets & reversals forum
Glycopyrrolate requires less maintenance treatments due to its effectivness.
To increase effectiveness with 'soft water' baking soda can be added to water to aid electrolytes (tiny particles that help the electric current travel through the water and into the skin).
You may want to custon build your own trays, for example use a deep container so the whole foot can be treated and not just the soles of your feet. use a small container just large enough to treat your hand, so if you are using glycopyrronium solution you do not have to use up too much. All that is needed is the tray and a stainless steel/aluminium metal strip to act as the electrode. Search ebay for "aluminium plates".
Information here on tray modifications: (thanks to superyou ESFB channel forum)
http://www.esfbchannel.com/phpBB2/viewt ... highlight=
*Studies show Iontophoresis with a 0.05% glycopyrronium bromide solution (or a stronger concentration) to be significantly superior to tap water in suppression of palmoplantar hyperhidrosis.
The solution can be ordered from a pharmacy.
http://www.ncbi.nlm.nih.gov/entrez/quer ... t=Abstract
Some more information - http://no-ets.com/forums/viewtopic.php?t=21
Anticholinergics are a class of medications that act by preventing acetylcholine from stimulating receptors on the sweat glands. In this way, anticholinergics shield the sweat gland from the action of acetylcholine. One anticholinergic, glycopyrrolate, is unlike the most others in that it does not cross the blood brain barrier and is therefore less likely to produce certain side effects.
*New/future treatment: Administering botox by iontophoresis
"Can be effective up to 3 months with only one treatment"
http://www.sweathelp.org/PDF/BotoxDeliv ... oresis.pdf
Machines:
Drionic
http://www.drionic.com/
Very useful site about the Driconic and alterations to any iontophoresis machines
http://www.geocities.com/drionicmods/index.html
Adding the option of an AC supply *recomended - http://www.geocities.com/drionicmods/nobatteries.html
Idrostar
http://www.i2m-labs.com/p_gb/index.htm
http://www.stdpharm.co.uk/ - idrostar machines can be bought from STD Pharmaceuticals, England.
People buying iontophoresis machines through the British NHS should have the cost greatly subsidised.
R.A. Fischer
http://www.rafischer.com/
http://www.esfbchannel.com/forum/index.html A posters successful treatment for feet
idromed 4
http://www.beathyperhidrosis.com/iontop ... oducts.htm
Instruction manual - http://photos.imageevent.com/otto/pdfma ... al_eng.pdf
I would strongly recommend the use of iontophoresis to treat Palmo-plantar hyperhidrosis. The underarms (axillary HH) and buttocks can also be treated with add on equipment available with the Driconic and Fischer machines.
If tap water iontophoresis does not work, glycopyrronium solution will most likely do the job unless in extremely severe cases. Even so, the new/future development of delivering Botox by iontophoresis means hand dryness may be obtained for up to 3 months, possibly even in the most severe cases. Obviously organised treatments of this nature means palmo-plantar Hyperhidrosis could potentially be eliminated.